Observations of growth plate development in achondroplastic (cn/cn) mice

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Observations of growth plate development in achondroplastic (cn/cn) mice.

The autosomal recessive gene for achondroplasia (cn) in the homozygous condition inhibits the growth of the cartilaginous skeleton in mice. Changes in the width of the proximal growth plate of the tibia and the caudal vertebrae and in the number of proliferative and hypertrophic cells were recorded in normal and achondroplastic (cn/cn) mice during the first 30 neonatal days. In normal mice as i...

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ژورنال

عنوان ژورنال: Reproduction Nutrition Développement

سال: 1981

ISSN: 0181-1916

DOI: 10.1051/rnd:19810715